OneG-Vali

OneG-Vali


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Detection, estimation and validation of cryptic intermediates.

Enter the PDB ID:
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pH:
Temperature: K
Solvent: H2O D2O Others
Ionic Strength: Low High
Enter the reference rates if the solvent is other than D2O: ka kb kw
Do you want to account for the effect of pKR of amino acids in the calculation ? Yes No
Upload the file containing the kex values (in min-1) of amino acids:
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Upload the ΔGHX of the residues:



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Multistate melting curve analysis using experimental parameters.



Updated on May 8, 2015
for queries contact:
sivaram @ scbt.sastra.edu
tricha @ bioinfo.sastra.edu
Please cite the website and the following reference(s) in your publication(s) if you use OneG–Vali.
1. T. Richa and T. Sivaraman. OneG–Vali: a computational tool for detecting, estimating and validating cryptic intermediates of proteins under native conditions. RSC Adv. (2014), 4(68):36325-36335.
2. T. Richa, Computational tools for predicting cryptic intermediates and metastable states in the unfolding kinetics of proteins under native conditions. Ph.D. Dissertation (2014), SASTRA University, Tamil Nadu, India.